Genetic disruption of PPAR decreases the tumorigenicity of human colon cancer cells
نویسندگان
چکیده
منابع مشابه
Gastrin gene expression is required for the proliferation and tumorigenicity of human colon cancer cells.
The majority of human colon cancers express the gastrin gene, and a significant percentage bind gastrin-like peptides. However, it is not known if gastrin gene products are physiologically relevant to the growth and proliferation of human colon cancers. To investigate the functional role of gastrin gene expression, we examined the effect of gastrin antisense (AS) RNA expression on the growth an...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2001
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.051630998